![]() ![]() This markedly altered brain fluid transport in AQP4 KO mice may result from a reduction in glymphatic clearance, leading to enlargement and stagnation of fluid in the interstitial space. The larger interstitial fluid volume likely resulted in increased slow but not fast MR diffusion measures and coincided with reduced glymphatic influx. ![]() AQP4 KO mice had larger interstitial spaces and total brain volumes resulting in higher water content and reduced CSF space volumes, despite similar CSF production rates and vascular density compared to wildtype mice. Here, we used high-resolution 3D magnetic resonance (MR) non-contrast cisternography, diffusion-weighted MR imaging (MR-DWI) along with intravoxel-incoherent motion (IVIM) DWI, while evaluating glymphatic function using a standard dynamic contrast-enhanced MR imaging to better understand how water transport and glymphatic function is disrupted after genetic deletion of AQP4. Yet, no studies have systematically examined how these abnormalities in structure and water transport correlate with glymphatic function. ![]() Mice with genetic deletion of AQP4 (AQP4 KO) exhibit abnormalities in the brain structure and molecular water transport. CSF transport is facilitated by the expression of aquaporin-4 (AQP4) water channels on the perivascular endfeet of astrocytes. I think they mean “dangerously volatile."īut they had to go and be ableist about it for some misbegotten reason.The glymphatic system is a fluid transport network of cerebrospinal fluid (CSF) entering the brain along arterial perivascular spaces, exchanging with interstitial fluid (ISF), ultimately establishing directional clearance of interstitial solutes. Also OP has no clue what schizophrenia is. She’s provoked by her love for Satoshi and Satoko. Shion Sonozaki, male Yangire: Russia, Kaitou Sai / X and Reisuke Houjo,įamous Yanderes: Gasai Yuno, Katsura Kotonoha,Kaede Fuyo,Shion Sonozaki, male Yandere: Psyche ( Izaya Orihara ),Rolo ( some might not be considered yandere or yangire it depends on your point of view of course. ![]() such as wanting to hold onto their happy feeling” Also adding emphasis that they must seem sweet/innocent/happy-carefree normally until provoked.įamous Yangire: Rena Ryuuguu. They also don’t necessarily have to be provoked to enter their Psycho-state, but can switch for reasons observers would be hard-pressed to determine. Their motivation, if they have one, can vary immensely. the Yangire character is not driven by an obsessive need to possess a friend or lover. Yangire: basically a Yandere without the romantic interest. ironically, contradicting to the image above a Yandere often even kills their beloved one if it seems that they aren’t loved back by their loved one or if their loved one seems to cheat on them. often turns out to be a stalker in attempt to stay always close to their loved ones. Can appear normal until provoked, or just be unstable to begin with. Yandere: someone who is obsessed/possessive to an unhealthy extent with/of a romantic interest. This behavior is different from that of a Yandere character in regard to the motivation that sparked the change in the character. Yangire is a combination of the two words yanderu, meaning to be sick, and kire or gire, meaning to cut, slice, or “to snap”. Yangire- refers to characters who snap suddenly out of jealousy, irritation or something similar. ![]()
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |